ACAP2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-9166	Proteintech Group Inc 140291AP150UL	150 μL

Description

The low density lipoprotein (LDL) receptor system coordinates the metabolism of cholesterol, an essential component of the plasma membrane of all mammalian cells. Study of this system has led to an enhanced understanding of the cellular basis of cholesterol homeostasis. It has also brought into focus an important mechanism of metabolic regulation-the process of receptor-mediated endocytosis. Data suggest that the juxtamembranous region of the cytoplasmic domain participates in protein:protein interactions that allow the low density lipoprotein receptor to cluster in coated pits. It has been shown that the family of LDL receptors may serve as viral receptors. Endocytosis of the Flaviviridae viruses, hepatitis C virus, GB virus C/hepatitis G virus, and bovine viral diarrheal virus (BVDV) was shown to be mediated by LDL receptors on cultured cells.

Specifications

• Antigen: ACAP2
• Applications: Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: Q15057, Q5FVC7, Q6ZQK5
• Gene ID (Entrez): 23527, 619382, 78618
• Immunogen: ACAP2 Fusion Protein Ag5190
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: ACAP2

• Concentration: 0.15 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: ACAP2, Centaurin beta 2, CENTB2, CNT B2, KIAA0041
• Gene Symbols: Acap2
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody