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Actin (Muscle Specific) Antibody (HHF35 + MSA/953), DyLight 550, Novus Biologicals™
SDP

Catalog No. NBP247663R Shop All R&D Systems Products
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Catalog No. NBP247663R Supplier Novus Biologicals Supplier No. NBP247663R
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Description

Mouse Monoclonal Antibody

Actin (Muscle Specific) Monoclonal specifically detects Actin (Muscle Specific) in Human, Rat, Rabbit samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.

Specifications

Antigen Actin (Muscle Specific)
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone HHF35 + MSA/953
Conjugate DyLight 550
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Accession No. P62736, P68133, P68032
Gene Alias ACTA, ACTC, actin, alpha 2, smooth muscle, aorta, actin, alpha cardiac muscle 1, actin, alpha skeletal muscle, actin, aortic smooth muscle, ACTSA, alpha-cardiac actin, ASD5, ASMA, Cell growth-inhibiting gene 46 protein, CFTD, CFTD1, CFTDM, CMD1R, CMH11, MPFD, NEM1, NEM2, NEM3, nemaline myopathy type 3
Gene Symbols ACTA1
Host Species Mouse
Immunogen Recombinant human actin fragment
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Angiogenesis, Cancer, Cell Biology, Cellular Markers, Cytoskeleton Markers, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 58
Test Specificity This antibody recognizes actin of skeletal, cardiac, and smooth muscle cells. It is not reactive with other mesenchymal cells except for myoepithelium. Actin can be resolved on the basis of its isoelectric points into three distinctive components: alpha, beta, and gamma in order of increasing isoelectric point. Anti-muscle specific actin recognizes alpha and gamma isotypes of all muscle groups. Non-muscle cells such as vascular endothelial cells and connective tissues are non-reactive. Also, neoplastic cells of non-muscle-derived tissue such as carcinomas, melanomas, and lymphomas are negative. It stains tumors of smooth muscle (leiomyomas and leiomyosarcomas) as well as skeletal muscle (rhabdomyomas and rhabdomyosarcomas).
Target Species Human, Rat, Rabbit
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG1 κ
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