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AF4 Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
$151.31
Specifications
Antigen | AF4 |
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Applications | Immunohistochemistry, Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Form | Liquid |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-156-2370
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Bethyl Laboratories, Inc
A302344AT |
20 μL |
Each of 1 for $151.31
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Description
The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Proto-oncogene AF-4 (or FEL) is a product of a chromosomal aberration of the human gene AFF1, which is associated with acute leukemias. The fusion of AF-4 on chromosome band 4q21 with the mixed lineage leukemia (MLL or HRX) gene on 11q23 results in a MLL-AF-4 chimeric transcription factor in which AF-4 contributes transcriptional effector properties and requires cell-specific accessory factors. MLL is involved in several chromosomal translocations associated with acute myeloid and lymphoid leukemia. The MLL-AF-4 fusion protein is expressed in all normal hematopoietic cells.Specifications
AF4 | |
Polyclonal | |
Liquid | |
RUO | |
TBS with 0.1% BSA and 0.09% sodium azide | |
MIXED LINEAGE LEUKEMIA, TRANSLOCATED TO, 2, ALL1 FUSED GENE FROM CHROMOSOME 4, AF4, FEL | |
AFF1 | |
IgG | |
Antigen affinity chromatography | |
Antibody |
Immunohistochemistry, Western Blot | |
Unconjugated | |
Rabbit | |
Human | |
P51825 | |
4299 | |
Between 1 and 50 | |
Primary | |
4° C | |
AFF1 |
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