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Tocris Bioscience™ AG 490
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Catalog No. 041410
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Quantity:
10 mg
50 mg
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Catalog No. 04-141-0

Supplier: Tocris Bioscience™ 0414/10

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Description

EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor

Selective inhibitor of EGF receptor tyrosine kinase (IC50 values are 2 and 13.5 μM for EGFR and ErbB2 respectively). Inhibitor of JAK2, JAK3/STAT, JAK3/AP-1 and JAK3/MAPK pathways and potently inhibits cytokine-independent cell growth in vitro and tumor cell invasion in vivo.

Chemical Identifiers

CAS 133550-30-8
Molecular Formula C17H14N2O3

Specifications

Quantity 10 mg
Formula Weight 294.31
Purity >99%
Molecular Weight (g/mol) 294.31
Chemical Name or Material AG 490

Safety and Handling

Recommended Storage Store at Room Temperature
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