Aggrecan Antibody (MK-302), Novus Biologicals™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
NB019421	Novus Biologicals NBP2296700.025ML	0.025 mL
NBP229670	Novus Biologicals NBP229670	0.1 mL

Description

Aggrecan Monoclonal specifically detects Aggrecan in Human, Mouse, Rat, Bovine, Canine, Rabbit, Sheep samples. It is validated for Western Blot, ELISA, Radioimmunoassay.

Specifications

• Antigen: Aggrecan
• Dilution: Western Blot 1:100-1:2000, ELISA 1:100-1:5000, Radioimmunoassay 1:100-1:200
• Classification: Monoclonal
• Form: Ascites
• Regulatory Status: RUO
• Target Species: Rat, Human, Sheep, Canine, Rabbit, Bovine, Mouse
• Gene Accession No.: P16112
• Gene ID (Entrez): 176
• Immunogen: Chondroitinase ABC-digested adult human aggrecan.
• Primary or Secondary: Primary
• Content And Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

• Clone: MK-302
• Applications: ELISA, Western Blot, Radioimmune Assays (RIA)
• Conjugate: Unconjugated
• Host Species: Mouse
• Research Discipline: Extracellular Matrix, Growth and Development, Mesenchymal Stem Cell Markers, Neuronal Cell Markers, Neuronal Stem Cell Markers, Stem Cell Markers
• Formulation: Ascites with No Preservative
• Gene Alias: AGC1SEDK, aggrecan, aggrecan core protein, Cartilage-specific proteoglycan core protein, Chondroitin sulfate proteoglycan 1, Chondroitin sulfate proteoglycan core protein 1, CSPCP, CSPG1aggrecan 1, CSPGCP, large aggregating proteoglycan, MSK16AGCAN
• Gene Symbols: ACAN
• Isotype: IgG1
• Purification Method: Unpurified
• Test Specificity: Reacts with a wide range of cartilage proteoglycans after either chondroitinase (ABC or AC) or testicular hyaluronidase digestion. Native proteoglycans do not react with MAB2035. Antibody binding to epitope is successfully inhibited by disaccharides of chondroitin-6-sulfate. Recognizes the chondroitin-6-sulfate stubs (preferentially in clusters) of high density cartilage proteoglycans of different species. No cross-reactivity with dermatan sulfate, keratan sulfate or chondroitin-4-sulfate.

For Research Use Only