DescriptionAIB1-AC3 recognizes AIB1, a member of the SRC-1 family of nuclear receptor coactivators with an apparent molecular weight of 160kDa. The AIB1 gene has been mapped to region 20q12 and has been shown to be amplified in breast tumors and pancreatic cancer cell lines. AIB1 interacts in a ligand-dependent fashion with the estrogen receptor to enhance estrogen-dependent transcriptional gene activation.
|AIB1 / SRC-3|
|ChIP Assay, Western Blot|
|This AIB1 antibody was raised against a peptide derived from human AIB1/SRC-3.|
|-20°C, Avoid Freeze/Thaw Cycles|
|70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8|
|2010305B15Rik; ACTR; AIB1; AIB-1; Amplified in breast cancer 1 protein; amplified in breast cancer-1 protein homolog; AW321064; BHLHE42; CAGH16; CBP-interacting protein; Class E basic helix-loop-helix protein 42; CTG26; KAT13B; MGC141848; NCOA3; NCoA-3; Nuclear receptor coactivator 3; OTTHUMP00000031716; p/Cip; pCIP; RAC3; RAC-3; Receptor-associated coactivator 3; RP5-1049G16.3; Src3; SRC-3; Steroid receptor coactivator protein 3; Thyroid hormone receptor activator molecule 1; TNRC14; TNRC16; TRAM1; TRAM-1|
|Antigen affinity chromatography|
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