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AIF-1/Iba1 Antibody (rAIF1/1909), Biotin, Novus Biologicals™
SDP

Catalog No. NB008946 Shop All R&D Systems Products
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NB008946 0.1 mL
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Catalog No. NB008946 Supplier Novus Biologicals Supplier No. NBP275760B
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Description

Mouse Monoclonal Antibody

AIF-1/Iba1 Monoclonal specifically detects AIF-1/Iba1 in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen AIF-1/Iba1
Applications Immunohistochemistry, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone rAIF1/1909
Conjugate Biotin
Dilution Immunohistochemistry, Immunohistochemistry-Paraffin
Formulation PBS with 0.05% Sodium Azide
Gene Alias AIF-1, allograft inflammatory factor 1, G1, IBA1, IbaI, interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, IRT1, IRT-1, Protein G1
Gene Symbols AIF1
Host Species Mouse
Immunogen Purified recombinant human AIF-1/Iba1 protein (around aa 1-146) (exact sequence is proprietary) (Uniprot: P55008)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Autoimmune Diseases, Cancer, Cell Biology, Cell Cycle and Replication, Immunology, Inflammation, Lipid and Metabolism, Microglia Markers, Neuroscience
Primary or Secondary Primary
Test Specificity AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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