AIF-1/Iba1 Antibody (rAIF1/1909), DyLight 488, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP275760G

Catalog No. NB008951

Description

AIF-1/Iba1 Monoclonal specifically detects AIF-1/Iba1 in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: AIF-1/Iba1
• Classification: Monoclonal
• Conjugate: DyLight 488
• Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
• Gene Symbols: AIF1
• Immunogen: Purified recombinant human AIF-1/Iba1 protein (around aa 1-146) (exact sequence is proprietary) (Uniprot: P55008)
• Quantity: 0.1 mL
• Research Discipline: Autoimmune Diseases, Cancer, Cell Biology, Cell Cycle and Replication, Immunology, Inflammation, Lipid and Metabolism, Microglia Markers, Neuroscience
• Test Specificity: AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).
• Content And Storage: Store at 4°C in the dark.

• Applications: Immunohistochemistry, Immunohistochemistry (Paraffin)
• Clone: rAIF1/1909
• Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin
• Gene Alias: AIF-1, allograft inflammatory factor 1, G1, IBA1, IbaI, interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, IRT1, IRT-1, Protein G1
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Isotype: IgG1 κ