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ALDH18A1/P5CS Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501568720
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50-156-8720 10 μL
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Catalog No. 50-156-8720 Supplier Bethyl Laboratories, Inc Supplier No. A304803AT
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Orangutan

This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.

Specifications

Antigen ALDH18A1/P5CS
Applications Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene ALDH18A1
Gene Accession No. P54886
Gene Alias ALDH18A1; aldehyde dehydrogenase 18 family, member A1; GSAS; MGC117316; P5CS; PYCS; aldehyde dehydrogenase 18A1; delta1-pyrroline-5-carboxlate synthetase; pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde synthetase)
Gene Symbols ALDH18A1
Host Species Rabbit
Immunogen Between 745 and 795
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5832
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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