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  6. Alkaline Phosphatase/ALPP Antibody (ALPP/516) - Azide and BSA Free, Novus Biologicals™

Alkaline Phosphatase/ALPP Antibody (ALPP/516) - Azide and BSA Free, Novus Biologicals™
SDP

Catalog No. NBP247991B Shop All R&D Systems Products
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NBP247991B 0.2 mg
NBP247991A 0.1 mg
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Catalog No. NBP247991B Supplier Novus Biologicals Supplier No. NBP2479910.2MG

Description

Mouse Monoclonal Antibody

Alkaline Phosphatase/ALPP Monoclonal antibody specifically detects Antigen in Human samples. It is validated for Flow Cytometry, Immunofluorescence, Immunohistochemistry (Frozen).

Specifications

Antigen Alkaline Phosphatase/ALPP
Applications Flow Cytometry, Immunohistochemistry (Frozen), Immunofluorescence, CyTOF
Classification Monoclonal
Clone ALPP/516
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Frozen : 1.0 - 2.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
Formulation PBS with No Preservative
Gene Alias Alkaline phosphatase Regan isozyme, alkaline phosphatase, placental, alkaline phosphatase, placental (Regan isozyme), alkaline phosphatase, placental type, alkaline phosphomonoesterase, ALP, EC 3.1.3.1, FLJ61142, glycerophosphatase, PALP, Placental alkaline phosphatase 1, PLAP, PLAP-1, Regan isozyme
Gene Symbols ALPP
Host Species Mouse
Immunogen Recombinant full-length human ALPP protein
Molecular Weight of Antigen 70 kDa
Purification Method Protein A or G purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Cancer, Embryonic Stem Cell Markers, Ovarian Carcinoma Cell Markers, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 250
Test Specificity PLAP is a tissue specific, trophoblast-derived, 70kDa, glycosyl-phosphatidylinositol (GPI)-anchored, dimeric, Zn2+ metallo-glycoprotein that catalyzes the hydrolysis of phosphomonoesters into an inorganic phosphate and an alcohol. It is present in the placenta and serum of pregnant women and in high frequency in gynecological and testicular cancers and in lower frequency in other tumors. The three tissue-specific AP's in humans, PLAP, germ cell AP (GCAP) and intestinal AP, are 90-98% homologous. Non-tissue specific AP is found in kidney, liver and bone. This MAb binds equally well to all common allelic variants (S, F, FS and I) of PLAP and to some variants of AP from normal human testis. This MAb can be used as tracer antibody in ELISA to detect PLAP in serum of S, F, FS and I phenotypes.
Target Species Human
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG1 κ
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