Invitrogen™ alpha COP Recombinant Rabbit Monoclonal Antibody (3W6Y6)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA537942

Catalog No. PIMA537942

Description

Positive Samples: HeLa, HT-29, MCF7, Mouse lung, Rat brain Immunogen sequence: MLTKFETKSA RVKGLSFHPK RPWILTSLHN GVIQLWDYRM CTLIDKFDEH DGPVRGIDFH KQQPLFVSGG DDYKIKVWNY KLRRCLFTLL GHLDYIRTTF.

In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms.

Specifications

• Antigen: alpha COP
• Classification: Recombinant Monoclonal
• Concentration: 0.25 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P53621, Q8CIE6
• Gene Symbols: COPA
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human COPA (P53621).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 3W6Y6
• Conjugate: Unconjugated
• Gene: COPA
• Gene Alias: AILJK; alpha coat protein; alpha-coat protein; Alpha-COP; AU040324; coatomer protein complex subunit alpha; coatomer subunit alpha; COPA; HEPCOP; HEP-COP; proxenin; xenin; Xenopsin-related peptide
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12847, 1314, 304978
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid