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  6. alpha-Methylacyl-CoA Racemase/AMACR Antibody, Novus Biologicals™

alpha-Methylacyl-CoA Racemase/AMACR Antibody, Novus Biologicals™
SDP

Catalog No. NBP232916B Shop All R&D Systems Products
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0.1 mg
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Catalog No. Quantity
NBP232916B 0.2 mg
NBP232916F 0.02 mg
NBP232916A 0.1 mg
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Catalog No. NBP232916B Supplier Novus Biologicals Supplier No. NBP2329160.2MG

Description

Rabbit Polyclonal Antibody

alpha-Methylacyl-CoA Racemase/AMACR Polyclonal antibody specifically detects Antigen in Human samples. It is validated for Immunohistochemistry (Paraffin), Western Blotting.

Specifications

Antigen alpha-Methylacyl-CoA Racemase/AMACR
Applications Western Blot, Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
Dilution Western Blot 1:100-1:200, Immunohistochemistry-Paraffin 1:50-1:100
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Accession No. Q9UHK6
Gene Alias 2-methylacyl-CoA racemase, alpha-methylacyl-CoA racemase, CBAS4, EC 5.1.99.4, RACE, RM
Gene Symbols AMACR
Host Species Rabbit
Immunogen A synthetic peptide from human AMACR protein
Molecular Weight of Antigen 54 kDa
Purification Method Protein A purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Lipid and Metabolism, Prostate Cancer, Signal Transduction
Primary or Secondary Primary
Gene ID (Entrez) 23600
Test Specificity This antibody recognizes a protein of 54kDa, which is identified as AMACR, also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies ha
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG
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