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  8. AMN 082 dihydrochloride, Tocris Bioscience™

AMN 082 dihydrochloride, Tocris Bioscience™
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Catalog No. 238550
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective mGlu7 agonist

AMN 082 dihydrochloride is a the first selective mGlu7 agonist. Potently inhibits cAMP accumulation and stimulates GTPγS binding in recombinant cells and on membranes expressing mGlu7 (EC50 = 64 - 290 nM). Selective over other mGluR subtypes and selected ionotropic glutamate receptors up to 10 μM. Acts via a novel allosteric site and is orally active and brain penetrant. Reduces haloperidol-induced catalepsy in rats.

View important information regarding the usage of AMN 082 dihydrochloride .

Chemical Identifiers

CAS 97075-46-2
Molecular Formula C28H30Cl2N2
Molecular Weight (g/mol) 465.462
InChI Key YRQCDCNQANSUPB-UHFFFAOYSA-N
Synonym amn082 dihydrochloride, amn 082 dihydrochloride, n,n'-dibenzhydrylethane-1,2-diamine dihydrochloride, amn hplc , solid, n,n'-bis diphenylmethyl-1,2-ethanediamine dihydrochloride, diphenylmethyl 2-diphenylmethyl amino ethyl amine dihydrochloride, n,n inverted exclamation marka-dibenzhydrylethane-1,2-diamine dihydrochloride
PubChem CID 11698390
IUPAC Name N,N'-dibenzhydrylethane-1,2-diamine;dihydrochloride
SMILES C1=CC=C(C=C1)C(C2=CC=CC=C2)NCCNC(C3=CC=CC=C3)C4=CC=CC=C4.Cl.Cl

Specifications

Quantity 50 mg
Formula Weight 465.45
Percent Purity >99%
Chemical Name or Material AMN 082 dihydrochloride

Safety and Handling

Recommended Storage Desiccate at +4°C
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