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AMPD3 Antibody (AMPD3/901), Alexa Fluor™ 350, Novus Biologicals™
SDP

Catalog No. NP247691A30 Shop All R&D Systems Products
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NP247691A30 0.1 mL
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Catalog No. NP247691A30 Supplier Novus Biologicals Supplier No. NBP247691AF350
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Description

Mouse Monoclonal Antibody

AMPD3 Monoclonal specifically detects AMPD3 in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen AMPD3
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
Classification Monoclonal
Clone AMPD3/901
Conjugate Alexa Fluor 350
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence, Immunocytochemistry
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias adenosine monophosphate deaminase (isoform E), adenosine monophosphate deaminase 3, AMP aminohydrolase, AMP deaminase 3, AMP deaminase isoform E, EC 3.5.4.6, Erythrocyte AMP deaminase, erythrocyte type AMP deaminase, erythrocyte-specific AMP deaminase, myoadenylate deaminase
Gene Symbols AMPD3
Host Species Mouse
Immunogen Recombinant full-length human AMPD3 protein (Uniprot: Q01432)
Purification Method Protein A or G purified
Quantity 0.1 mL
Primary or Secondary Primary
Gene ID (Entrez) 272.0
Test Specificity It recognizes a protein of ∼90kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This monoclonal antibody shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This monoclonal antibody is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG2b κ
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