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AMPD3 Antibody (AMPD3/901), Novus Biologicals™
SDP

Catalog No. NBP24444100 Shop All R&D Systems Products
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NBP24444100 0.02 mg
NBP24444101 0.1 mg
NBP24444102 0.2 mg
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Catalog No. NBP24444100 Supplier Novus Biologicals Supplier No. NBP2444410.02MG
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Mouse Monoclonal Antibody

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence

AMPD3 Monoclonal specifically detects AMPD3 in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen AMPD3
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
Classification Monoclonal
Clone AMPD3/901
Concentration 0.2mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 1 - 2 ug/million cells in 0.1ml, Immunohistochemistry-Paraffin 2 - 4 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml, Immunocytochemistry 1 - 2.0 ug/ml
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Accession No. Q01432
Gene Alias adenosine monophosphate deaminase (isoform E), adenosine monophosphate deaminase 3, AMP aminohydrolase, AMP deaminase 3, AMP deaminase isoform E, EC 3.5.4.6, Erythrocyte AMP deaminase, erythrocyte type AMP deaminase, erythrocyte-specific AMP deaminase, myoadenylate deaminase
Gene Symbols AMPD3
Host Species Mouse
Immunogen Recombinant full-length human AMDP3 protein
Purification Method Protein A or G purified
Quantity 0.02 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 272
Test Specificity It recognizes a protein of ∼90kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG2b κ
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