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ANO3 Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 194891AP

Catalog No. 50-173-2410


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Description

Description

The protein encoded by this gene belongs to the TMEM16 family of predicted membrane proteins, that are also known as anoctamins. While little is known about the function of this gene, mutations in this gene have been associated with some cases of autosomal domit craniocervical dystonia. Cells from individuals with a mutation in this gene exhibited abnormalities in endoplasmic reticulum-dependent calcium signaling. Studies in rat show that the rat ortholog of this protein interacts with, and modulates the activity of a sodium-activated potassium channel. Deletion of this gene caused increased pain sensitivity in the rat model system. Alternative splicing results in multiple transcript variants encoding different isoforms.
Specifications

Specifications

ANO3
0.17 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
A2AHL1, Q9BYT9
ANO3, anoctamin 3, C11orf25, GENX 3947, TMEM16C, Transmembrane protein 16C
Rabbit
IgG
150 μL
-20°C
Primary
228432, 63982
Immunoprecipitation, Western Blot
Unconjugated
ANO3
Liquid
ANO3
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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