ANO3 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 194891AP
DescriptionThe protein encoded by this gene belongs to the TMEM16 family of predicted membrane proteins, that are also known as anoctamins. While little is known about the function of this gene, mutations in this gene have been associated with some cases of autosomal domit craniocervical dystonia. Cells from individuals with a mutation in this gene exhibited abnormalities in endoplasmic reticulum-dependent calcium signaling. Studies in rat show that the rat ortholog of this protein interacts with, and modulates the activity of a sodium-activated potassium channel. Deletion of this gene caused increased pain sensitivity in the rat model system. Alternative splicing results in multiple transcript variants encoding different isoforms.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|ANO3, anoctamin 3, C11orf25, GENX 3947, TMEM16C, Transmembrane protein 16C|
|Immunoprecipitation, Western Blot|
|Antigen Affinity Chromatography|
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