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  6. Annexin VII Mouse anti-Human, Unlabeled, Clone: 5, BD

Annexin VII Mouse anti-Human, Unlabeled, Clone: 5, BD

Catalog No. BDB610669 Shop All BD Biosciences Products
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BDB610669 150 μg
BDB610668 50 μg
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Catalog No. BDB610669 Supplier BD Biosciences Supplier No. 610669

Description

Mouse Monoclonal Antibody

Annexin VII, also known as synexin, is a member of the Annexin family characterized by Ca2+ dependent phospholipid binding. Annexins have a four-fold internal repeat of about 70 amino acids that contains the Ca2+-binding sites. They also have a regulatory NH2-terminal region of 30-40 amino acids. Annexin VII mRNA has been detected in many tissues and is most abundant in brain, heart, skeletal muscle, and lung. Annexin VII mRNA exhibits a tissue dependent polymorphism due to alternative splicing which results in two different isoforms of 47kDa and 51kDa. In vitro, Annexin VII aggregates chromaffin granules and enhances membrane fusion in a Ca2+ and GTP-dependent manner. Although the physiological role of Annexin VII is not completely understood, it is believed to influence and regulate Ca2+ dependent events such as secretion at the plasma membrane.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

TRUSTED_SUSTAINABILITY

Specifications

Antigen Annexin VII
Applications Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 5
Concentration 250μg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Purification Method Affinity Purified
Quantity 150 μg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Human
Isotype IgG1
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For Research Use Only.

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