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ATP Synthase α Mouse, Unlabeled, Clone: 51, BD

Mouse Monoclonal Antibody

$198.00

Specifications

Antigen ATP Synthase α
Isotype IgG2a
Immunogen Human ATP Synthase α aa. 113-220
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
BDB612516
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BD Biosciences
612516
50μg
Each for $198.00
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BDB612517
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BD Biosciences
612517
150μg This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

ATP synthase is a large enzyme complex that uses an electrochemical H+ or Na+ gradient to synthesize ATP from ADP and Pi, providing the organism with the ATP needed for energy. The complex consists of two major units, F0 and F1. F0 is embedded in the inner membrane of the mitochondria and, due to its hydrophobic nature, translocates protons across this membrane. F1 is the catalytic portion in the matrix region of the mitochondria and is comprised of α, β, γ, δ, and ε subunits at a 3:3:1:1:1 ratio. The α subunit is a ubiquitous protein that is highly conserved among species. It has an adenine specific binding site that binds both ATP and ADP. There are two glycine rich regions in the sequence, the A domain and B domain, that are thought to be part of the nucleotide binding domain. It has been demonstrated that the N-terminus of the α subunit is necessary for the correct functional and structural connection of F0 to F1. Thus, the α subunit is an essential component of the ATP synthase complex and plays a role in properly orienting the F0 and F1 units.

Immunofluorescence, Western Blotting

Specifications

Specifications

ATP Synthase α
Human ATP Synthase α aa. 113-220
Unconjugated
Cell Biology
Murine
Affinity Purified
Monoclonal
Store undiluted at -20°C.
IgG2a
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary
Western Blot
RUO
51
250μg/mL
SDS

For Research Use Only.

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