MilliporeSigma™ anti-c-Fos (Ab-2) (4-17), Polyclonal

Rabbit Polyclonal Antibody

Manufacturer:  MilliporeSigma™ PC05L100UG

Catalog No. PC05L100UG

Description

Specifically detects c-Fos (4-17) Clone: in Human, Mouse, Rat samples, and it is validated for Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Immuno Blotting

The proto-oncogenefos has been implicated in cell growth, differentiation and development. Fos is induced by a large number of stimuli including mitogens, differentiation-specific agents, pharmacological agents, etc. Induction of the 62,000 dalton fos protein is rapid but transient. The fos protein is associated with a 39,000 dalton protein which has been identified as the protein product of the jun proto-oncogene (c-jun). The fos/jun protein complex binds specifically to a sequence element in DNA referred to as the AP-1 binding site.

Specifications

• Antigen: c-Fos (4-17)
• Conjugate: Unconjugated
• Format: purified
• Immunogen: a synthetic peptide (SGFNADYEASSSRC) corresponding to amino acids 4-17 of human c-Fos
• Quantity: 100μg
• Storage Requirements: 2°C to 8°C
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human, Murine, Rat

• Applications: Immuno Blotting, Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
• Formulation: In 0.05M sodium phosphate buffer, 0.2% gelatin.
• Host Species: Rabbit
• Isotype: IgG
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes the ∽50-62kDa c-Fos protein in HepG2, NIH3T3, and MCF-7 cells.

For Research Use Only