MilliporeSigma anti-c-Fos (Ab-2) (4-17), Polyclonal
Rabbit Polyclonal Antibody
Manufacturer: MilliporeSigma PC05L100UG
Specifically detects c-Fos (4-17) Clone: in Human, Mouse, Rat samples, and it is validated for Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Immuno BlottingThe proto-oncogenefos has been implicated in cell growth, differentiation and development. Fos is induced by a large number of stimuli including mitogens, differentiation-specific agents, pharmacological agents, etc. Induction of the 62,000 dalton fos protein is rapid but transient. The fos protein is associated with a 39,000 dalton protein which has been identified as the protein product of the jun proto-oncogene (c-jun). The fos/jun protein complex binds specifically to a sequence element in DNA referred to as the AP-1 binding site.
|a synthetic peptide (SGFNADYEASSSRC) corresponding to amino acids 4-17 of human c-Fos|
|2°C to 8°C|
|Human, Murine, Rat|
|Immuno Blotting, Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation|
|In 0.05M sodium phosphate buffer, 0.2% gelatin.|
|Recognizes the ∽50-62kDa c-Fos protein in HepG2, NIH3T3, and MCF-7 cells.|
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