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Description
The 13-11 monoclonal antibody specifically recognizes Troponin T type 2 (cardiac), encoded by the gene TNNT2 . Troponin T is the tropomyosin-binding subunit of the troponin complex, which also encompasses troponin C and troponin I. This complex regulates muscle contraction in skeletal and cardiac muscle in response to alterations in calcium levels. Troponin T type 2 is solely found in the heart, and genetic alterations in the TNNT2 gene are associated to a series of heart disorders in humans, including hypertrophic cardiomyopathy, dilated cardiomyopathy and left ventricular noncompaction. Cardiac Troponin T can be used as a marker for the identification of cardiomyocytes derived from pluripotent stem cells.
Specifications
Specifications
| Antigen | Cardiac Troponin T |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | 13-11 |
| Conjugate | PE |
| Description | cTnT, Cardiac Muscle Troponin T, Troponin T type 2, TNNT2 |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Rabbit cardiac troponin T Protein |
| Purification Method | Affinity Purified |
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