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CD105 (Endoglin) Mouse anti-Human, PE, Clone: 266, BD

Catalog No. BDB560839 Shop All BD Biosciences Products
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BDB560839 100 Tests
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Catalog No. BDB560839 Supplier BD Biosciences Supplier No. 560839
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Description

Mouse Monoclonal Antibody

The 266 monoclonal antibody specifically binds to CD105. CD105 presents an integral membrane homodimer protein with subunits of 95 kDa found on vascular endothelial cells and syncytiotrophoblasts of placenta. CD105 is weakly expressed on stromal fibroblasts. It is also expressed on U937 cells, activated macrophages, and mesenchymal stem cells. CD105 is a component of the TGF-β receptor system in human umbilical vein endothelial cells and binds TGF-β1 and TGF-β3 with high affinity but does not bind toTGF-β2. Expression of CD105 is increased on activated endothelium in tissues undergoing angiogenesis, such as in tumors, or in cases of wound healing or dermal inflammation.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD105
Applications Flow Cytometry
Classification Monoclonal
Clone 266
Conjugate PE
Description Endoglin; ENG; END; HHT1; ORW; ORW1
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human Umbilical Vein Endothelial Cells
Purification Method Affinity Purified
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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