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CD11a (Integrin αL chain, LFA-1α) Mouse anti-Human, FITC, Clone: G-25.2, BD

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Catalog No. BDB347983 Supplier BD Biosciences Supplier No. 347983
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Description

Mouse Monoclonal Antibody

CD11a, clone G-25.2, is derived from hybridization of mouse Sp2/0 myeloma cells with spleen cells from BALB/c mice immunized with human cytotoxic T lymphocytes (CTL).

CD11a (Anti-LFA-1α) recognizes the Mr 180-kdalton (kDa) α chain of the leucocyte function–associated antigen-1 (LFA-1). LFA-1, a member of a subfamily of integrin receptors, is a leucocyte adhesion receptor that binds to an intercellular adhesion molecule (ICAM) on target tissues. This subfamily consists of three heterodimeric proteins that share a common noncovalently-associated β chain (CD18 antigen, Mr 95 kDa) but possess distinct α-subunits recognized by CD11a (anti-LFA-1α), CD11b (Leu-15), and CD11c (Leu-M5).

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD11a
Applications Flow Cytometry
Classification Monoclonal
Clone G-25.2
Concentration 6.25μg/mL
Conjugate FITC
Description LFA-1α
Formulation Phosphate buffered saline with gelatin and 0.1% sodium azide.
Host Species Mouse
Immunogen Human cytotoxic T lymphocytes
Quantity 100 Tests
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
Form Purified
Isotype IgG2a κ
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For Research Use Only.

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