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CD172a Rat anti-Mouse, FITC, Clone: P84, BD

Catalog No. BDB560316 Shop All BD Biosciences Products
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BDB560316 0.1 mg
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Catalog No. BDB560316 Supplier BD Biosciences Supplier No. 560316
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Description

Rat Monoclonal Antibody

The P84 monoclonal antibody specifically binds to CD172a, also known as SIgnal-Regulatory Protein α (SIRP α ), Src Homology 2 domain-containing protein tyrosine Phosphatase (SHP) Substrate 1 (SHPS-1), or Brain Immunoglobulin-like molecule with Tyrosine-based activation motifs (BIT). CD172a is an adhesion molecule of the Ig superfamily which is expressed on neurons in the central nervous system and the retina, on macrophages, and on bone-marrow myeloid cells. Its ligand, CD47, or Integrin-Associated Protein (IAP), is expressed by a wide variety of cells. CD172a and CD47 are proposed to mediate bi-directional signaling to modify neural synaptic activity and regulate the phagocytic activities of macrophages.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD172a
Applications Flow Cytometry
Classification Monoclonal
Clone P84
Concentration 0.5mg/mL
Conjugate FITC
Description Sirpa; Sirp alpha; Sirpα; Bit; SHPS-1; p84; Ptpns1
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen Membrane fractions from mouse brain
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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