Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. CD183 Mouse anti-Human, Unlabeled, Clone: 1C6/CXCR3, BD

CD183 Mouse anti-Human, Unlabeled, Clone: 1C6/CXCR3, BD

Catalog No. p-3844052 Shop All BD Biosciences Products
Change view
Click to view available options
Quantity:
0.1 mg
0.5 mg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
BDB557183 0.1 mg
BDB557184 0.5 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
Catalog No. BDB557183 Supplier BD Biosciences Supplier No. 557183
Only null left
Add to Cart
Add to Cart

Description

Mouse Monoclonal Antibody

Clone 1C6/CXCR3 reacts with the human form of the 40 - 41kDa seven-transmembrane protein and member of the G protein-coupled receptor family. CXCR3 is expressed primarily on activated T cells that infiltrate inflammatory sites. It has also been detected on some circulating T cells, B cells, and NK cells. Reports show that some CXCR3 T cells also express CCR5 and are mostly CD45RO cells. Three ligands for CXCR3 have been identified. They are interferon-γ inducible 10kDa protein (IP-10), monokine induced by interferon-γ (MIg), and interferon-inducible T-cell γ chemoattractant (I-TAC). These chemokines are produced by a variety of cells upon stimulation by IFN γ and interact with CXCR3 to mediate T-cell chemotaxis. This reagent has been reported to be suitable for immunohistochemical staining of acetone-fixed, frozen sections and/or formalin-fixed, paraffin-embedded tissue sections with citrate pretreatment. Clone CXCR3 also cross reacts with a subset of peripheral blood lymphocytes of baboon, and both rhesus and cynomolgus macaque monkeys. The distribution of lymphocytes is similar to that observed with peripheral blood lymphocytes from normal human donors. CXCR3 has been clustered as CD183 in the VIIth HLDA workshop. This product is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Mouse
Clone: 1C6/CXR3
Isotype: IgG1 κ
Species Reactivity: Human

Flow Cytometry, Functional Assay

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD183
Applications Flow Cytometry
Classification Monoclonal
Clone 1C6/CXCR3
Concentration 0.5mg/mL
Conjugate Unconjugated
Description CXCR3; C-X-C chemokine receptor type 3; GPR9; IP10R; MigR; CKRL2; CMKAR3
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human CXCR3 Peptide
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
Show More Show Less

For Research Use Only.

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.