CD205 Rat anti-Mouse, PE, Clone: 561118, Invitrogen™

Rat Monoclonal Antibody

Supplier:  Thermo Scientific MA523654

Catalog No. PIMA523654

Description

CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region. Further, CD205 also prompts the reduced proliferation of B lymphocytes. Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.

Specifications

• Antigen: CD205
• Classification: Monoclonal
• Conjugate: PE
• Gene: Ly75
• Gene Alias: RP23-10L17.4, CD205, DEC-205, ly-75, CLEC13B, GP200-MR6, DCL-1 fusion, LY75-CD302 fusion protein
• Host Species: Rat
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 17076
• Content And Storage: 4° C, store in dark, DO NOT FREEZE!
• Form: Liquid

• Applications: Flow Cytometry
• Clone: 561118
• Formulation: Buffered saline solution with BSA and 0.09% sodium azide
• Gene Accession No.: Q60767
• Gene Symbols: LY75
• Immunogen: E. coli-derived recombit mouse DEC-205/CD205 Cys216-Pro503
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2b