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CD205 Rat anti-Mouse, PE, Clone: 561118, Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MA523654

Catalog No. PIMA523654

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region. Further, CD205 also prompts the reduced proliferation of B lymphocytes. Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.
Specifications

Specifications

CD205
Monoclonal
PE
Ly75
Liquid
LY75
E. coli-derived recombit mouse DEC-205/CD205 Cys216-Pro503
Protein A/G
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
561118
Buffered saline solution with BSA and 0.09% sodium azide
Q60767
RP23-10L17.4, CD205, DEC-205, ly-75, CLEC13B, GP200-MR6, DCL-1 fusion, LY75-CD302 fusion protein
Rat
IgG2B
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
17076
Documents
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