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CD205 Rat anti-Mouse, PE, Clone: 561118, Invitrogen™

Catalog No. pima523654
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100 Tests
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Catalog No. Quantity
PIMA523654 100 Tests
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Catalog No. PIMA523654 Supplier Thermo Scientific Supplier No. MA523654

Description

Rat Monoclonal Antibody

CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region. Further, CD205 also prompts the reduced proliferation of B lymphocytes. Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD205
Applications Flow Cytometry
Classification Monoclonal
Clone 561118
Conjugate PE
Formulation Buffered saline solution with BSA and 0.09% sodium azide
Gene Ly75
Gene Accession No. Q60767
Gene Alias RP23-10L17.4, CD205, DEC-205, ly-75, CLEC13B, GP200-MR6, DCL-1 fusion, LY75-CD302 fusion protein
Gene Symbols LY75
Host Species Rat
Immunogen E. coli-derived recombit mouse DEC-205/CD205 Cys216-Pro503
Purification Method Protein A/G
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17076
Target Species Mouse
Content And Storage 4° C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2b
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