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CD23 Mouse anti-Human, FITC, Clone: M-L233, BD

Catalog No. BDB561146 Shop All BD Biosciences Products
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BDB561146 100 Tests
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Catalog No. BDB561146 Supplier BD Biosciences Supplier No. 561146
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Description

Mouse Monoclonal Antibody

The M-L233 antibody specifically binds to human CD23, the low affinity receptor for human IgE (FcεRII). CD23 is a type II membrane glycoprotein that can be expressed by B cells, monocytes, macrophages, eosinophils, platelets and dendritic cells. CD23 can mediate IgE-dependent cytotoxicity and phagocytosis by macrophages and eosinophils. Soluble CD23 (sCD23) can be released by CD23-positive cells as a result of proteolytic cleavage of membrane CD23. Larger fragments of sCD23 (e.g., 25-37 kDa) retain their IgE-binding capacity whereas smaller fragments (i.e., ≤ 12 kDa) do not. Soluble CD23 may have immunoregulatory effects on the growth and differentiation of B cells and other cell types.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD23
Applications Flow Cytometry
Classification Monoclonal
Clone M-L233
Conjugate FITC
Description FCER2; FcεRII; Low affinity immunoglobulin epsilon Fc receptor; BLAST-2
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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