MilliporeSigma™ anti-CD45, PE-Cy7, Clone: 30-F11,

Rat Monoclonal Antibody

Supplier:  MilliporeSigma™ MABF1465

Catalog No. MABF1465MI

Description

Specifically detects CD45 Clone: 30-F11 in Mouse samples, and it is validated for Flow Cytometry

The 30-F11 antibody reacts with mouse CD45, which is one of the most abundant hematopoietic markers and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others. The 30-F11 antibody is widely used as a leukocyte marker for B cells, T cell subsets and NK cell subsets.

Specifications

• Antigen: CD45
• Classification: Monoclonal
• Conjugate: PE-Cyanine7
• Gene Accession No.: P06800
• Host Species: Rat
• Purification Method: Purified by size-exclusion chromatography
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
• Isotype: IgG2b κ

• Applications: Flow Cytometry
• Clone: 30-F11
• Formulation: Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
• Gene Symbols: Ptprc, Ly-5
• Immunogen: Proprietary immunogen
• Quantity: 100 μg
• Research Discipline: Inflammation, Immunology
• Target Species: Mouse
• Form: Purified

For Research Use Only