CD46 Mouse anti-Bovine, Human, Biotin, Clone: MEM-258, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA119520

Catalog No. 01-676-254

Description

CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.

Specifications

• Antigen: CD46
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 15mM sodium azide; pH 7.4
• Gene Accession No.: Q6VE48, P15529
• Gene Alias: AHUS2, MCP, MGC26544, MIC10, TLX, TRA2.10
• Host Species: Mouse
• Isotype: IgG1
• Quantity: 100 μg
• Storage Requirements: 4° C, do not freeze
• Primary or Secondary: Primary
• Gene ID (Entrez): 280851, 4179

• Applications: Flow Cytometry
• Clone: MEM-258
• Conjugate: Biotin
• Gene: CD46
• Format: Liquid
• Gene Symbols: CD46
• Immunogen: T cell line HPB-ALL.
• Purification Method: Purified
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Monoclonal
• Target Species: Bovine, Human