ICAM-1 Mouse anti-Bovine, Human, Rat, Clone: MEM-111, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA119123
DescriptionCD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.
|PBS with 15mM sodium azide; pH 7.4|
|Q95132, P05362, Q00238|
|BB2, P3.58, ICAM-1, cell surface glycoprotein P3.58, intercellular adhesion molecule 1, human rhinovirus receptor, major group rhinovirus receptor|
|4° C, do not freeze|
|25464, 281839, 3383|
|ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot|
|Burkitt′s lymphoma cell line Raji.|
|Bovine, Human, Rat|
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