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IL-23 p19 Rat anti-Mouse, Clone: 320234, Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MA523793

Catalog No. PIMA523793


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Description

Description

This antibody recognizes an epitope in the p19 subunit. In ELISAs, this antibody does not cross-react with Recombinant mouse (rm) IL-23 p19, rmIL-23 R, rmIL-12 R beta, rmIL-12 p35, Recombinant human (rh) IL-23, rhIL-23 p19, Recombinant rat IL-12, rmIL-12 p40, rmIL-12 p40 homodimer, or rmIL-12. Reconstitute at 0.5 mg/mL in sterile PBS.

This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.
Specifications

Specifications

IL-23 p19
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
Q9EQ14
IL12B, Il12p40, interleukin 12B, RP23-388G23.1, Il-12b, Il-12p40, p40, IL-12 p40, IL-23 subunit p40
Rat
IgG2a
500 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
83430
ELISA, Western Blot
320234
Unconjugated
Il23a
Lyophilized
IL23A
E. coli-derived recombit mouse IL-23
Protein A/G
RUO
Antibody
Monoclonal
Mouse
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