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MilliporeSigma™ anti-Lipoic Acid, Polyclonal
Rabbit Polyclonal Antibody
Supplier: MilliporeSigma™ 437695100UL
Description
Specifically detects Lipoic Acid Clone: in Many Species samples, and it is validated for ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immuno Blotting
Lipoic acid is a sulfur-containing substance that is readily converted to and from its reduced form, dihydrolipoic acid. It acts as a coenzyme in reactions that occur in the Krebs cycle; specifically it is involved in the decarboxylation of pyruvate and some other alpha-keto acids. Protein-bound lipoic acids such as E2 subunits,α-ketoglutarate dehydrogenase, or pyruvate dehydrogenase have been shown to be highly susceptible to free radical-derived oxidative modification. Lipoic acid is able to deactivate both fat and water soluble free radicals and thereby protect both lipoproteins and membranes; no other anti-oxidant can do this. It has also shown great promise in the treatment of HIV and in diabetes.
Specifications
Lipoic Acid | |
Polyclonal | |
serum diluted in buffer, 50% glycerol, pH 7.5. | |
lipoic acid conjugated to KLH | |
RUO | |
Recognizes native lipoic acid. Does not recognize lipoic acid modified by 4-HNE (4-hydroxy-2-noneal) and other lipid peroxidation products. | |
≤ -70°C | |
IgG |
ELISA, Immunoblot, Immunoblot, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin) | |
Unconjugated | |
Rabbit | |
100 μL | |
Primary | |
Multi-species | |
Diluted |
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Product Title
For Research Use Only
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