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MilliporeSigma™ anti-Lipoic Acid, Polyclonal

Rabbit Polyclonal Antibody

Supplier:  MilliporeSigma™ 437695100UL

Catalog No. 43-769-5100UL


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Description

Description

Specifically detects Lipoic Acid Clone: in Many Species samples, and it is validated for ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immuno Blotting

Lipoic acid is a sulfur-containing substance that is readily converted to and from its reduced form, dihydrolipoic acid. It acts as a coenzyme in reactions that occur in the Krebs cycle; specifically it is involved in the decarboxylation of pyruvate and some other alpha-keto acids. Protein-bound lipoic acids such as E2 subunits,α-ketoglutarate dehydrogenase, or pyruvate dehydrogenase have been shown to be highly susceptible to free radical-derived oxidative modification. Lipoic acid is able to deactivate both fat and water soluble free radicals and thereby protect both lipoproteins and membranes; no other anti-oxidant can do this. It has also shown great promise in the treatment of HIV and in diabetes.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Lipoic Acid
Polyclonal
serum diluted in buffer, 50% glycerol, pH 7.5.
lipoic acid conjugated to KLH
RUO
Recognizes native lipoic acid. Does not recognize lipoic acid modified by 4-HNE (4-hydroxy-2-noneal) and other lipid peroxidation products.
≤ -70°C
IgG
ELISA, Immunoblot, Immunoblot, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Unconjugated
Rabbit
100 μL
Primary
Multi-species
Diluted
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