MilliporeSigma™ anti-Lipoic Acid, Polyclonal

Rabbit Polyclonal Antibody

Supplier:  MilliporeSigma™ 437695100UL

Catalog No. 43-769-5100UL

Description

Specifically detects Lipoic Acid Clone: in Many Species samples, and it is validated for ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immuno Blotting

Lipoic acid is a sulfur-containing substance that is readily converted to and from its reduced form, dihydrolipoic acid. It acts as a coenzyme in reactions that occur in the Krebs cycle; specifically it is involved in the decarboxylation of pyruvate and some other alpha-keto acids. Protein-bound lipoic acids such as E2 subunits,α-ketoglutarate dehydrogenase, or pyruvate dehydrogenase have been shown to be highly susceptible to free radical-derived oxidative modification. Lipoic acid is able to deactivate both fat and water soluble free radicals and thereby protect both lipoproteins and membranes; no other anti-oxidant can do this. It has also shown great promise in the treatment of HIV and in diabetes.

Specifications

• Antigen: Lipoic Acid
• Classification: Polyclonal
• Formulation: serum diluted in buffer, 50% glycerol, pH 7.5.
• Immunogen: lipoic acid conjugated to KLH
• Regulatory Status: RUO
• Test Specificity: Recognizes native lipoic acid. Does not recognize lipoic acid modified by 4-HNE (4-hydroxy-2-noneal) and other lipid peroxidation products.
• Content And Storage: ≤ -70°C
• Isotype: IgG

• Applications: ELISA, Immunoblot, Immunoblot, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Multi-species
• Form: Diluted

For Research Use Only