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anti-IFN-alpha D, Clone: N27, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP142171

Catalog No. NBP142171


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Description

Description

IFN-alpha 1 Monoclonal antibody specifically detects IFN-alpha 1 in Mouse, Rat samples. It is validated for Western Blot, ELISA, Block/Neutralize.
Specifications

Specifications

IFN-alpha D
N27
Unconjugated
PBS with 0.05% Sodium Azide
Purified
IFNA1
The antibody reacts with the IFN-Alpha antigen.
22 kDa
0.1 mg
Cancer, Immunology, Innate Immunity
Primary
3439
Mouse, Rat
Blocking Assay, ELISA, Western Blot
0.1 mg/mL
Western Blot 1:100-1:2000, ELISA 1:100-1:2000, Blocking/Neutralizing 50-200 molar excess
P01562
IFL, IFN, IFNA13, IFNAalphaIFN-alpha-1/13, IFN-ALPHA, IFN-alpha 1b, IFN-alphaD, interferon alpha 1b, interferon alpha-1/13, Interferon alpha-D, interferon, alpha 1, LeIF D, MGC138207, MGC138505, MGC138507
Mouse
IgG1 Kappa
Protein A or G purified
RUO
Store at 4C. Do not freeze.
Monoclonal
The alpha interferons are involved in virus resistance in target cells for these viruses. They are known to block cell proliferation and to regulate MHC class I antigen expression. The IFNalpha family has pseudogenes in two families (I and II), one with a mature length of 166aa and one of 172aa. Cells producing IFNalpha are lymphocytes, monocytes, macrophages and cell lines such as Namalwa and KGI. Bioassays for IFNalpha include cytopathic effect blocking, by viruses such as VSV, SFV and BMCV, on their target cells. A number of receptors for IFNalpha are now known and seem to be expressed on most cell types. N27 is specific for INFalpha(II) and does not cross react with INFalpha(I). Source: A BALB/c mouse was immunized with E-coli derived, purified recombinant IFN-alpha 2c and spleen cells were fused with mouse myeloma cells NS1.
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