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IFN-alpha 1 Mouse anti-Human, Mouse, Rat, Clone: N27, Novus Biologicals™
SDP

Catalog No. NBP142171 Shop All R&D Systems Products
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NBP142171 0.1 mg
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Catalog No. NBP142171 Supplier Novus Biologicals Supplier No. NBP142171

Description

Mouse Monoclonal Antibody

IFN-alpha 1 Monoclonal antibody specifically detects IFN-alpha 1 in Human, Mouse, Rat samples. It is validated for Western Blot, ELISA, Immunohistochemistry (Frozen), Block/Neutralize.

Specifications

Antigen IFN-alpha D
Applications Western Blot, ELISA, Blocking Assay
Classification Monoclonal
Clone N27
Concentration 0.1 mg/mL
Conjugate Unconjugated
Dilution Western Blot 1:100-1:2000, ELISA 1:100-1:2000, Blocking/Neutralizing 50-200 molar excess
Gene Accession No. P01562
Gene Alias IFL, IFN, IFNA13, IFNAalphaIFN-alpha-1/13, IFN-ALPHA, IFN-alpha 1b, IFN-alphaD, interferon alpha 1b, interferon alpha-1/13, Interferon alpha-D, interferon, alpha 1, LeIF D, MGC138207, MGC138505, MGC138507
Gene Symbols IFNA1
Host Species Mouse
Immunogen The antibody reacts with the IFN-Alpha antigen.
Molecular Weight of Antigen 22 kDa
Purification Method Protein A or G purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Cancer, Immunology, Innate Immunity
Primary or Secondary Primary
Gene ID (Entrez) 3439
Test Specificity The alpha interferons are involved in virus resistance in target cells for these viruses. They are known to block cell proliferation and to regulate MHC class I antigen expression. The IFNalpha family has pseudogenes in two families (I and II), one with a mature length of 166aa and one of 172aa. Cells producing IFNalpha are lymphocytes, monocytes, macrophages and cell lines such as Namalwa and KGI. Bioassays for IFNalpha include cytopathic effect blocking, by viruses such as VSV, SFV and BMCV, on their target cells. A number of receptors for IFNalpha are now known and seem to be expressed on most cell types. N27 is specific for INFalpha(II) and does not cross react with INFalpha(I). Source: A BALB/c mouse was immunized with E-coli derived, purified recombinant IFN-alpha 2c and spleen cells were fused with mouse myeloma cells NS1.
Target Species Human, Mouse, Rat
Content And Storage Store at 4C. Do not freeze.
Form Purified
Isotype IgG1 κ
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