NMDAR2B Mouse, Unlabeled, Clone: 13, BD

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
BDB610416	BD Biosciences 610416	50 μg
BDB610417	BD Biosciences 610417	150 μg

Description

The majority of synapses in the central nervous system utilize glutamate as a neurotransmitter to produce rapid neuronal excitation. Glutamate has a diverse array of receptors that can be categorized into two groups: ionotropic and metabotropic. The ionotropic receptors are subdivided into two distint types: 1) receptors for N-methyl D-aspartate (NMDAR) and 2) non-NMDA receptors for AMPA and kainate. Three types of NMDAR2 have been identified: NR2A, NR2B, and NR2C. NR2A and NR2B contain a C-terminal extension (>600 amino acids) that has small scattered regions of conserved sequence. The three NR2 mRNAs show overlapping, differential expression patterns in the rat brain. NR2B has been reported to be expressed in the forebrain, thalamic nuclei, amygdaloid nuclei, caudateputamen, and in restricted regions of the olfactory bulb.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Specifications

• Antigen: NMDAR2B
• Concentration: 250μg/mL
• Classification: Monoclonal
• Host Species: Mouse
• Research Discipline: Cell Biology
• Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
• Isotype: IgG2b
• Purification Method: Affinity Purified
• Description: N-Methyl-D-Aspartate Receptor 2B

• Clone: 13
• Applications: Western Blot
• Conjugate: Unconjugated
• Regulatory Status: RUO
• Target Species: Human, Mouse, Rat
• Immunogen: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at -20°C.

For Research Use Only.