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TFIIB Mouse, Unlabeled, Clone: 24, BD
Mouse Monoclonal Antibody
Specifications
| Antigen | TFIIB |
|---|---|
| Clone | 24 |
| Concentration | 250μg/mL |
| Applications | Immunofluorescence, Immunoprecipitation, Western Blot |
| Classification | Monoclonal |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|
BDB610462
|
BD Biosciences
610462 |
50 μg | Item Discontinued This item has been discontinued by the supplier. Please Sign In to view product availability in your area. | N/A | |||||
|
BDB610463
|
BD Biosciences
610463 |
150 μg | Item Discontinued This item has been discontinued by the supplier. Please Sign In to view product availability in your area. | N/A | |||||
Description
TFIIB is a ubiquitous factor required for transcription initiation by RNA polymerase II. Studies suggest that TFIIB serves as a bridge between the “TATA”-binding factor (TFIID) and RNA polymerase II during pre-initiation complex assembly and that TFIIB can be a target of acidic activators. An essential component of the machinery that transcribes protein-coding genes, the three-dimensional structure of the human TFIIB appears to consist of two direct repeats that adopt similar alpha-helical folds, conferring pseudo-twofold symmetry. An extensive, central basic surface, including an amphipathic alpha helix, is critical to the function of TFIIB as a bridge between the TBP-promoter complex and transcription factors. TFIIB has a calculated molecular weight of 33kDa and has been reported to be observed to migrate between 33-40kDa.
Immunofluorescence, Immunoprecipitation, Western Blotting
Specifications
| TFIIB | |
| 250μg/mL | |
| Monoclonal | |
| Mouse | |
| Cell Biology | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| IgG2a | |
| Affinity Purified |
| 24 | |
| Immunofluorescence, Immunoprecipitation, Western Blot | |
| Unconjugated | |
| RUO | |
| Canine, Frog, Human, Mouse, Rat | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| Primary |
For Research Use Only.
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