TREM1 Rat anti-Mouse, Clone: 174031, Invitrogen
Rat Monoclonal Antibody
Manufacturer: Invitrogen MA523885
In Western blots, no cross-reactivity with recombit mouse TREM-2B, recombit human (rh) TREM-1, or rhTREM-2 is observed. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.TREM1 (triggering receptor expressed on myeloid cells 1) is a receptor belonging to the Ig superfamily that amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. It is thought that TREM1 other related TREM proteins such as TREM2 act to modulate the inflammatory response. TREM1 has also been linked to inflammatory bowel disease resulting in enhanced production of TNF, IL-6, IL-8, and MCP-1.
|PBS with 5% trehalose and No Preservative|
|TREM1, Triggering receptor expressed on myeloid cells 1, triggering receptor expressed on monocytes 1, TREM-1, CD354|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Functional Assay, Immunocytochemistry, Immunofluorescence, Western Blot|
|Mouse myeloma cell line NS0-derived recombit mouse TREM-1 Ala21-Ser202|
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