β-Tubulin Mouse, Alexa Fluor 488, Clone: 5H1, BD

Catalog No.	Quantity
BDB558605	100 Tests

Catalog No. BDB558605 Supplier BD Biosciences Supplier No. 558605

Description

Mouse Monoclonal Antibody

Tubulin is a highly conserved protein with a molecular weight of ∽50 kD. The self-assembly of tubulin leads to microtubules, hollow cylinders that are one of the major components of the eukaryotic cytoskeleton. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton. There are two main classes of tubulin isoforms, α - and β -tubulin, which are usually products of separate genes. Microtubules are made from protofilaments, strings of alternating α - and β -tubulin spaced 4nm apart and pointing in the same direction. Tubulin can be posttranslationally modified in several ways, including phosphorylation, acetylation, glutamylation, and detyrosination. For example, microtubules that turn over slowly tend to be acetylated and detyrosinated.

Specifications

• Antigen: β-Tubulin
• Applications: In vitro Assay
• Classification: Monoclonal
• Clone: 5H1
• Conjugate: Alexa Fluor 488
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Host Species: Mouse
• Purification Method: Affinity Purified
• Quantity: 100 Tests
• Regulatory Status: RUO
• Research Discipline: Cell Biology
• Primary or Secondary: Primary
• Target Species: Chinese Hamster, Human, Indian Muntjac, Mouse, Rat, Syrian Hamster
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
• Isotype: IgM κ