β-Tubulin Mouse, Alexa Fluor 488, Clone: 5H1, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 558605

Catalog No. BDB558605

Description

Tubulin is a highly conserved protein with a molecular weight of ∽50 kD. The self-assembly of tubulin leads to microtubules, hollow cylinders that are one of the major components of the eukaryotic cytoskeleton. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton. There are two main classes of tubulin isoforms, α - and β -tubulin, which are usually products of separate genes. Microtubules are made from protofilaments, strings of alternating α - and β -tubulin spaced 4nm apart and pointing in the same direction. Tubulin can be posttranslationally modified in several ways, including phosphorylation, acetylation, glutamylation, and detyrosination. For example, microtubules that turn over slowly tend to be acetylated and detyrosinated.

Specifications

• Antigen: β-Tubulin
• Classification: Monoclonal
• Conjugate: Alexa Fluor 488
• Host Species: Mouse
• Quantity: 100 Tests
• Research Discipline: Cell Biology
• Target Species: Chinese Hamster, Human, Indian Muntjac, Mouse, Rat, Syrian Hamster
• Isotype: IgM κ

• Applications: In vitro Assay
• Clone: 5H1
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.