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Ubc9 Mouse, Unlabeled, Clone: 50, BD

Mouse Monoclonal Antibody

$213.00 - $427.00

Specifications

Antigen Ubc9
Isotype IgG2a
Immunogen Human Ubc9 aa. 26-156
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
BDB610748
View Documents
BD Biosciences
610748
50μg
Each for $213.00
Add to cart
 
BDB610749
View Documents
BD Biosciences
610749
150μg
Each for $427.00
Add to cart
 
Description

Description

Progression of the mammalian cell cycle is primarily regulated by phosphorylation/dephosphorylation and synthesis/degradation of many key proteins. Ubiquitin, a soluble protein of 76 amino acids, is enzymatically attached to an e-NH2-Lys in a target protein. Ubiquitination is a hallmark for rapid protein degradation of the target protein in the proteosome (a cytoplasmic complex of proteases). Human homologs of the yeast ubiquitin-conjugating enzymes (Ubc) have been reported, including Ubc9. Ubc9 is 158 amino acids with an apparent molecular weight of 18kDa. Although ubiquitously expressed, the highest levels of Ubc9 are found in testis and thymus. Ubc9 was localized to the synaptonemal complex in male mouse sex chromosomes. Furthermore, Ubc9 interacts with the recombination protein Rad51, thus suggesting an important role for Ubc9 during meiosis.
Specifications

Specifications

Ubc9
Human Ubc9 aa. 26-156
Unconjugated
Cell Biology
Mouse
Affinity Purified
Monoclonal
Store undiluted at -20°C.
IgG2a
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary
Western Blot
RUO
50
250μg/mL
SDS
Product Certifications

For Research Use Only.

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