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Arginase 1/ARG1/liver Arginase Antibody (ARG1/1125) - IHC-Prediluted, Novus Biologicals™
SDP

Catalog No. NBP248229 Shop All R&D Systems Products
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7 mL
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NBP248229 7 mL
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Catalog No. NBP248229 Supplier Novus Biologicals Supplier No. NBP248229
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Description

Mouse Monoclonal Antibody

Arginase 1/ARG1/liver Arginase Monoclonal specifically detects Arginase 1/ARG1/liver Arginase in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Arginase 1/ARG1/liver Arginase
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone ARG1/1125
Conjugate Unconjugated
Dilution Immunohistochemistry-Paraffin
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias arginase 1, arginase, liver, arginase-1, EC 3.5.3.1, Liver-type arginase, Type I arginase
Gene Symbols ARG1
Host Species Mouse
Immunogen Recombinant human Arginase 1/ARG1/liver Arginase protein fragment (around aa11-97) (exact sequence is proprietary) (Uniprot: P05089)
Molecular Weight of Antigen 36.5 kDa
Purification Method Protein A or G purified
Quantity 7 mL
Regulatory Status RUO
Research Discipline Cancer, Cellular Markers, Chromatin Research, Lipid and Metabolism, Myeloid derived Suppressor Cell
Primary or Secondary Primary
Gene ID (Entrez) 383
Test Specificity Recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG3 κ
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