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ARID1A/BAF250 Polyclonal Antibody, Bethyl Laboratories

Catalog No. p-7140599
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50-155-9092 20 μL
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Catalog No. 50-155-9092 Supplier Bethyl Laboratories, Inc Supplier No. A301041AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Specifications

Antigen ARID1A/BAF250
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene ARID1A
Gene Accession No. O14497
Gene Alias BAF250, C1orf4, AT rich interactive domain 1A SWI-like, B120, P270, SMARCF1, ELD, OSA1, hELD, hOSA1, BAF250a, MRD14, BM029
Gene Symbols ARID1A
Host Species Rabbit
Immunogen Between 750 and 800
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8289
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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