Armenian Hamster anti-CTLA-4, Clone: 1B8, Novus Biologicals
Armenian Hamster Monoclonal Antibody
Manufacturer: Novus Biologicals NBP1410000.1MG
DescriptionCTLA-4 Monoclonal antibody specifically detects CTLA-4 in Mouse samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunoprecipitation.
|PBS (pH 7.4) with 0.09% Sodium Azide|
|Extracellular portion of mouse CD152 fused to a mouse IgG2a.|
|Protein G purified|
|Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.|
|This antibody recognises mouse CD152, commonly known as CTLA-4 (cytotoxic T-lymphocyte protein 4), a structural homolog for CD28. CD152 binds the same ligands as CD28, namely CD80 (B7.1) and CD86 (B7.2), but with much higher affinity. However, while binding of CD28 enhances T cell function, binding of CD152 inhibits it. CD152 is not detected on naive T-cells and is induced upon T-cell activation.|
|ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot|
|Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:100, ELISA 1:100-1:2000, Immunocytochemistry/Immunofluorescence 1:10-1:2000, Immunoprecipitation 1:10-1:500|
|CD, CD152 antigen, CD152IDDM12, CD28, celiac disease 3, CELIAC3, CTLA-4, cytotoxic T-lymphocyte antigen 4, cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, cytotoxic T-lymphocyte-associated protein 4, cytotoxic T-lymphocyte-associated serine esterase-4, GRD4, GSE, ICOS, ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4|
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