CTLA-4 Antibody (1B8) - BSA Free, Novus Biologicals™

Armenian Hamster Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
NB018515	Novus Biologicals NBP1410000.025MG	0.025 mg
NBP14100001	Novus Biologicals NBP1410000.1MG	0.1 mg

Description

CTLA-4 Monoclonal specifically detects CTLA-4 in Mouse samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunoprecipitation.

Specifications

• Antigen: CTLA-4
• Concentration: 1.0 mg/mL
• Applications: Immunofluorescence, Immunoprecipitation, Immunocytochemistry, Flow Cytometry, Western Blot, ELISA
• Conjugate: Unconjugated
• Host Species: Armenian Hamster
• Research Discipline: Signal Transduction
• Formulation: PBS (pH 7.4) with 0.09% Sodium Azide
• Gene Alias: CD, CD152 antigen, CD152IDDM12, CD28, celiac disease 3, CELIAC3, CTLA-4, cytotoxic T-lymphocyte antigen 4, cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, cytotoxic T-lymphocyte-associated protein 4, cytotoxic T-lymphocyte-associated serine esterase-4, GRD4, GSE, ICOS, ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
• Gene Symbols: CTLA4
• Isotype: IgG
• Purification Method: Protein G purified
• Test Specificity: This antibody recognises mouse CD152, commonly known as CTLA-4 (cytotoxic T-lymphocyte protein 4), a structural homolog for CD28. CD152 binds the same ligands as CD28, namely CD80 (B7.1) and CD86 (B7.2), but with much higher affinity. However, while binding of CD28 enhances T cell function, binding of CD152 inhibits it. CD152 is not detected on naive T-cells and is induced upon T-cell activation.

• Clone: 1B8
• Dilution: Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:100, ELISA 1:100-1:2000, Immunocytochemistry/Immunofluorescence 1:10-1:2000, Immunoprecipitation 1:10-1:500
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Target Species: Mouse
• Gene Accession No.: P09793
• Gene ID (Entrez): 1493
• Immunogen: Extracellular portion of mouse CD152 fused to a mouse IgG2a.
• Primary or Secondary: Primary
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

For Research Use Only