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ASC2 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501557565
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50-155-7565 20 μL
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Catalog No. 50-155-7565 Supplier Bethyl Laboratories, Inc Supplier No. A300411AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist- and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins.

Specifications

Antigen ASC2
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene NCOA6
Gene Accession No. Q14686
Gene Alias activating signal cointegrator 2, activating signal cointegrator-2, AIB3, amplified in breast cancer protein 3, amplified in breast cancer-3 protein, ASC2, ASC-2, cancer-amplified transcriptional coactivator ASC-2, KIAA0181, NRC, NRC RAP250, nuclear receptor coactivator RAP250, nuclear receptor-activating protein, 250 kDa, peroxisome proliferator-activated receptor interacting protein, peroxisome proliferator-activated receptor-interacting protein, PPAR-interacting protein, PRIP, RAP250, thyroid hormone receptor binding protein, thyroid hormone receptor-binding protein, TRBP
Gene Symbols NCOA6
Host Species Rabbit
Immunogen Between 2000 and C-term
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23054
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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