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Invitrogen™ ASXL1 Polyclonal Antibody
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Catalog No. PIPA578646
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100 μL
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PIPA578646 100 μL
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Catalog No. PIPA578646 Supplier Invitrogen™ Supplier No. PA578646
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Description

Rabbit Polyclonal Antibody

Positive Control: human ASXL1-transfected 293T cells Predicted Reactivity: Mouse (93%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Probable Polycomb group (PcG) protein involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator of RARA and RXRA through association with NCOA1. Acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner; the function seems to involve differential recruitment of methylated histone H3 to respective promoters. Acts as corepressor for PPARG and suppresses its adipocyte differentiation-inducing activity. Non-catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1).
TRUSTED_SUSTAINABILITY

Specifications

Antigen ASXL1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Asxl1
Gene Accession No. P59598, Q8IXJ9
Gene Alias additional sex combs like 1; additional sex combs like 1, transcriptional regulator; additional sex combs like transcriptional regulator 1; additional sex combs-like protein 1; Asxl1; BOPS; KIAA0978; MDS; MGC117280; MGC71111; mKIAA0978; Polycomb group protein ASXL1; putative Polycomb group protein ASXL1; RGD1561878
Gene Symbols Asxl1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the N-terminus region of human ASXL1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171023, 228790
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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