Ataxin 2 Rabbit anti-Human, Mouse, Rat, Biotin, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-7224	100 μL

Catalog No. 50-173-7224 Supplier Proteintech Group Inc Supplier No. BIOTIN21776100UL

Description

Rabbit Polyclonal Antibody

The autosomal domit cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. Defects in this gene are the cause of spinocerebellar ataxia type 2 (SCA2). SCA2 belongs to the autosomal domit cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, ophthalmoplegia, bulbar and extrapyramidal signs, peripheral neuropathy and dementia. SCA2 is caused by expansion of a CAG repeat in the coding region of this gene. Longer expansions result in earlier onset of the disease. Alternatively spliced transcript variants encoding different isoforms have been identified but their full length sequence has not been determined.

Specifications

• Antigen: Ataxin 2
• Applications: Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 0.31 mg/mL
• Conjugate: Biotin
• Formulation: PBS with 50% glycerol and 0.05% Proclin 300; pH 7.3
• Gene: ATXN2
• Gene Accession No.: O70305, Q99700
• Gene Alias: ataxin 2, ATX2, ATXN2, FLJ46772, SCA2, TNRC13
• Gene Symbols: Atxn2
• Host Species: Rabbit
• Immunogen: Ataxin 2 Fusion Protein Ag16470
• Purification Method: Antigen Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 20239, 288663, 6311
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG