Invitrogen™ ATG10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA585722

Catalog No. PIPA585722

Description

Keep as concentrated solution. Positive Control: SK-N-SH, LoVo. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

ATG10 is involved in autophagy which is a process for the bulk degradation of cytosolic compartments by lysosomes/vacuoles. The formation of autophagosomes involves a dynamic rearrangement of the membrane for which two ubiquitin-like modifications (the conjugation of APG12p and the modification of a soluble form of MAP-LC3 to a membrane-bound form) are essential. APG10 is an E2-like enzyme involved in two ubiquitin-like modifications essential for autophagosome formation, ATG12 -ATG5 conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A), a homolog of yeast Apg8, to a membrane-bound form. The protein ATG10 is ubiquitously expressed and the human APG10L gene is localized on chromosome 5q14.2.

Specifications

• Antigen: ATG10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ATG10
• Gene Alias: 5330424L23Rik; 5430428K15Rik; Agp10; AI852123; APG10; APG10L; APG10-like; Apg10p; ATG10; ATG10 autophagy related 10 homolog; Atg10l; autophagy related 10; autophagy related 10 homolog; autophagy-related 10; autophagy-related protein 10; DKFZp586I0418; FLJ13954; mAPG10; pp12616; Ubiquitin-like-conjugating enzyme ATG10
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 83734
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.13 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q9H0Y0
• Gene Symbols: ATG10
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ATG10.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov