ATX2/SCA2 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-155-9304	Bethyl Laboratories, Inc A301118AT	20 μL

Description

The recommended shelf life for this product is 1 year from date of receipt.

The autosomal domit cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. Defects in this gene are the cause of spinocerebellar ataxia type 2 (SCA2). SCA2 belongs to the autosomal domit cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, ophthalmoplegia, bulbar and extrapyramidal signs, peripheral neuropathy and dementia. SCA2 is caused by expansion of a CAG repeat in the coding region of this gene. Longer expansions result in earlier onset of the disease. Alternatively spliced transcript variants encoding different isoforms have been identified but their full length sequence has not been determined.

Specifications

• Antigen: ATX2/SCA2
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Alias: TNRC13, ATX2, SCA2, ataxin 2, ASL13, ATXN2
• Immunogen: Between 1262 and 1312
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Gene: ATXN2

• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: O70305, Q99700
• Gene ID (Entrez): 20239, 6311
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody