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Invitrogen™ BAF53A Recombinant Rabbit Monoclonal Antibody (5H3L6)

Catalog No. PI702414
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100 μg
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PI702414 100 μg
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Catalog No. PI702414 Supplier Invitrogen™ Supplier No. 702414
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Description

Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with Monkey, Pig, Rat Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

BAF53A is a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BAF53A
Applications Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 5H3L6
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene Actl6a
Gene Accession No. O96019, Q9Z2N8
Gene Alias 2810432C06Rik; 53 kDa BRG1-associated factor A; actin like 6A; actin-like 6; actin-like 6A; actin-like 6B; actin-like protein 6A; actin-related protein 4; actin-related protein Baf53a; Actl6; Actl6a; ACTL6B; AI851094; ARP4; ArpNbeta; ARPN-BETA; BAF complex 53 kDa subunit; BAF53; Baf53a; BAF53B; BRG1/brm-associated factor 53A; BRG1-associated factor 53A; C79802; hArpN alpha; hArpN beta; INO80 complex subunit K; INO80K; MGC5382; MGC5382 Arp4; RGD1307747
Gene Symbols Actl6a
Host Species Rabbit
Immunogen Peptide corresponding to human BAF53A (aa124-142).
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 361925, 56456, 86
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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