BAF57/SMARCE1 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-155-8505	Bethyl Laboratories, Inc A300810AT	20 μL

Description

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.

Specifications

• Antigen: BAF57/SMARCE1
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Alias: SMARCE1; BAF57; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1; mammalian chromatin remodeling complex BRG1-associated factor 57; BAF57; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin e1
• Immunogen: Between 360 and C-term
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Gene: SMARCE1

• Applications: Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: O54941, Q969G3
• Gene ID (Entrez): 57376, 6605
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody