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Bax Antibody (2D2), Alexa Fluor™ 532, Novus Biologicals™
SDP

Catalog No. NP233092A32 Shop All R&D Systems Products
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NP233092A32 0.1 mL
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Catalog No. NP233092A32 Supplier Novus Biologicals Supplier No. NBP233092AF532
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Description

Mouse Monoclonal Antibody

Bax Monoclonal specifically detects Bax in Human, Monkey, Mouse (Negative), Rat (Negative) samples. It is validated for Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

Antigen Bax
Applications Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 2D2
Conjugate Alexa Fluor 532
Dilution Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias apoptosis regulator BAX, BCL2-associated X protein, Bcl2-L-4, BCL2L4bcl2-L-4, Bcl-2-like protein 4
Gene Symbols BAX
Host Species Mouse
Immunogen A synthetic peptide, aa 3-16 (Cys-GSGEQPRGGGPTSS) of human bax protein. (Uniprot: Q07812)
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Apoptosis, Cancer, Core ESC Like Genes, Stem Cell Markers, Tumor Suppressors
Primary or Secondary Primary
Gene ID (Entrez) 581.0
Test Specificity Recognizes a protein of 21kDa, identified as the Bax protein. This monoclonal antibody is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
Target Species Human, Monkey, Mouse, Rat
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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